"坎坷崎岖的路" can be translated into English as "a rough and bumpy road" or "a rugged and uneven path".
"Rough and bumpy" emphasizes the unevenness and difficulty of traversing the road.
"Rugged and uneven" conveys a similar sense of a difficult, unpaved, or irregular terrain.
Both expressions capture the essence of a challenging or difficult journey, whether metaphorically or literally.