"坎坷崎岖的路" can be translated into English as "a rough and bumpy road" or "a rugged and uneven path".
Both expressions convey the idea of a difficult, uneven, or challenging journey, with the first option ("a rough and bumpy road") being more commonly used in everyday English to describe a challenging or troublesome situation or route. The second option ("a rugged and uneven path") emphasizes the unevenness and difficulty of the terrain more vividly.