“具有讽刺意味的事”可以翻译为 “an ironic situation/incident/event” 或者 “a case of irony” 。
例如：
It's an ironic situation that the person who advocated for simplicity now lives in such a luxurious mansion.（那个曾倡导简约生活的人，如今却住在如此奢华的宅邸里，这真是一件具有讽刺意味的事。）
The fact that he missed the train due to being stuck in traffic, after having boasted about always being on time, is a classic case of irony.（他吹嘘自己总是准时，结果却因堵车而错过了火车，这真是一个典型的具有讽刺意味的事。）