“洁癖的”常见英文表达是 “fastidious about cleanliness” 或更简洁的 “meticulously clean-obsessed”（不过此表述较非正式，正式语境中较少用），最常用且自然的表达是 “obsessive about cleanliness” ，这里 “obsessive” 意思是“着迷的；痴迷的；有洁癖的” ，用来描述人在清洁方面有过度、执着的倾向。
例句：
He is obsessive about cleanliness and spends hours every day cleaning his house.（他有洁癖，每天都要花好几个小时打扫房子。）
She has a fastidious attitude towards cleanliness, always wiping surfaces multiple times.（她对清洁有洁癖般的态度，总是要把表面擦好多遍 。）