“向相反方向”常见的英文表达有 "in the opposite direction" 或 "towards the opposite direction"。
In the opposite direction：更常用、更自然，例如：
The two cars were moving in the opposite direction.（两辆车朝相反方向行驶。）
Turn around and walk in the opposite direction.（转身，朝相反方向走。）
Towards the opposite direction：语法正确，但稍显正式或书面化，例如：
The birds flew towards the opposite direction of the storm.（鸟儿朝着风暴相反的方向飞去。）
根据语境选择即可，日常交流中 "in the opposite direction" 更常用。