“粗大的一端”可以翻译为 "the thicker end" 或 "the thicker part (at one end)",具体使用可根据语境调整。例如:
The stick has a thicker end and a thinner end.(这根棍子有一端粗大,另一端细小。)
Hold the stick by its thicker part.(握住棍子粗大的一端。)