“没精打采的样子”可以用英语表达为 “a listless/lethargic look/appearance” 或 “looking/appearing listless/lethargic”。
Listless：意为“无精打采的，缺乏活力的”，常用来形容人或动物的状态。
Lethargic：意为“昏昏欲睡的，无精打采的”，也常用来描述人或动物因疲倦、疾病或其他原因而表现出的缺乏活力的状态。
例如：
He had a listless look on his face, as if he didn't care about anything.（他脸上露出没精打采的样子，好像对什么都不在乎。）
She was looking lethargic after a long day at work.（工作了一整天后，她看起来没精打采的。）