“反对党领导”可以翻译为 “oppose the leadership of the Party” 或者 “be opposed to the Party's leadership” 。
例句：
We must firmly oppose any behavior that opposes the leadership of the Party.（我们必须坚决反对任何反对党领导的行为。）
Those who are opposed to the Party's leadership will ultimately fail.（那些反对党领导的人最终将会失败 。 ）