“显著变化”常见的英文表达有 "significant change" 、"marked change" 或 "notable change" 。
significant change：是最常用、最通用的表达，强调变化的重要性、程度大且具有实际意义。例如：There has been a significant change in the market trends over the past year.（过去一年里市场趋势发生了显著变化。）
marked change：侧重于变化明显、易于察觉。例如：The patient showed a marked change in his condition after the treatment.（治疗后，病人的状况有了明显变化。）
notable change：指值得注意、引人关注的变化。例如：There has been a notable change in the climate patterns in recent decades.（近几十年来，气候模式发生了值得注意的变化 。）