“幽默感”常见的英文表达是 a sense of humor（美式英语）或 a sense of humour（英式英语，拼写上“humour”比“humor”多了一个“u”）。
He has a great sense of humor and always makes us laugh.（他很有幽默感，总是能让我们开怀大笑。）
She's known for her sharp sense of humour.（她以敏锐的幽默感而闻名。）