“自毁”常见的英文表达有 self-destruction（名词形式）和 self-destruct（动词形式）。具体如下：
self-destruction：名词，指自我毁灭的行为、过程或状态。例如：
His obsession with revenge led him to a path of self-destruction.（他对复仇的执念让他走上了自我毁灭的道路。）
The company's mismanagement brought about its own self-destruction.（公司的管理不善导致了自身的毁灭。）
self-destruct：动词，表示自我毁灭、自行销毁，常指物体、计划、事业等因自身原因而失败或被破坏，也可用于比喻人因自身行为而走向毁灭。例如：
The missile is programmed to self-destruct if it misses its target.（如果导弹没有击中目标，它就会被设定为自行销毁。）
His constant self-doubt and negative thinking caused him to self-destruct emotionally.（他持续的自我怀疑和消极想法让他在情感上自我毁灭了。）