“使苦恼的东西”可以翻译为“something that causes distress” 或者更简洁地表达为“a source of distress” 。“distress”有“苦恼；忧虑；痛苦”之意，这两个表达都能准确传达出“使某人苦恼的事物”这一含义。
例句：
Financial problems have been a source of distress for him recently.（最近经济问题一直让他很苦恼。）
The constant noise from the construction site is something that causes him great distress.（建筑工地持续不断的噪音让他十分苦恼 。）